Effects of amfetamines 

 

The pharmacological effects of amfetamine use include:

• locomotor stimulation

• euphoria and excitement (such as hyperactivity and increased confidence)

• appetite suppression

• insomnia

• increased stamina

• decreased fatigue

• piloerection

• increased blood pressure

• inhibition of GI motility

• increased libido

 

Adverse effects can also occur, such as anxiety, irritability, restlessness, panic and paranoia

 

Chronic use can result in cognitive and psychomotor impairment, psychosis, depression and severe dental problems due to teeth grinding, gingivitis, increased soft drink consumption while under the influence and a lack of dental hygiene.

 

After stopping the drug, the user sleeps heavily, feels lethargic and can be anxious, depressed and hungry.

 

The mortality rate is lower for amfetamines compared with opioids, but they are taken for a longer period of time and there is an increased likelihood of the drugs being injected, which can result in death due to MI, seizure, arrhythmia and respiratory failure.